Summary written by USA Jobs 24 from AstraZeneca's advert and our data on 16,911 current US jobs. How we check every job
At a glance
AstraZeneca is hiring a Self Healing Supply Chain Senior Director in United States. It is a full-time role in Operations & Supply Chain, asking for at least 10 years of experience, first listed on November 10. The advertised pay is $177,653–$266,479 a year. The description mentions Agile and SAP. AstraZeneca has 88 other openings in the US. Across all employers on USA Jobs 24 there are 854 Operations openings in the US today; the typical one asks for 5 years and advertises about $142,000 a year at the midpoint.
How the pay compares
AstraZeneca advertises $177,653 to $266,479 a year, a midpoint of $222,066 a year. Where an offer lands in a range usually depends on experience and on the exact location. That is higher than about 89% of the 449 operations jobs across the US that publish a yearly rate on USA Jobs 24, where the typical midpoint is $142,000 a year. To see roughly what this leaves after federal and state tax, try our take-home pay calculator.
Skills in this advert
How often each skill named in this advert appears across the 854 operations jobs we list today. SAP is the most widely requested (10% of jobs), while Agile is the least common (5%). Widely requested skills are what employers expect as a baseline; rarer ones show what is special about this job.
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Before you apply
- Check it is still open. We found this job on AstraZeneca's Workday site on November 10 and checked it again November 10, 5:17 AM ET. When an employer takes a job down, we remove it at our next daily update.
- Check the location works for you. This role is based in United States. If you would need to move, ask whether relocation help is offered.
- Match the experience. The advert asks for at least 10 years of experience. If you are a little short, a close match on the skills in the advert can still win an interview.
- Tailor your resume. Use the advert's own words, such as Agile and SAP, wherever they are true for you. Our resume guide shows how.
- Know your number. Decide the lowest offer you would accept before the first call. Our salary negotiation guide explains how to ask for more.
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About hiring at AstraZeneca
AstraZeneca has 89 openings on USA Jobs 24 today across 8 states. Most are in healthcare & pharma (29), data & AI (11) and software & IT (9). The biggest locations are Boston, MA (8), Minneapolis, MN (1) and St. Louis, MO (1). None of them is fully remote, 11% are open to entry-level candidates and 74% show pay. We collect AstraZeneca's jobs every day straight from its own careers system (Workday), never from job boards or agencies.
The employer's advert
This is AstraZeneca's own description of the job, copied word for word from its careers site. We have not edited it.
Show the full advert from AstraZenecaHide the advert996 words
Self Healing Supply Chain Program Sr. Director (SHSCPD)
Gaithersburg, MD
Global Supply Chain
Hybrid Work- on average 3 days/week in office
Are you ready to lead one of the most aspiring AI-driven supply chain transformations in our industry? As Senior Director of the Self-Healing Supply Chain program, you will shape how a global biopharmaceutical supply chain senses disruption, makes better decisions and learns from every outcome, so that patients receive the medicines they need, when they need them.
The Self-Healing Supply Chain (SHSC) program is a core part of our Intelligent Supply ambition. It follows a Sense, Assess, Heal and Learn loop, using AI and end-to-end enterprise data to detect issues, assess impact, simulate scenarios, recommend actions and learn from outcomes. The program brings together Decision Intelligence, a supply chain digital twin and knowledge graph, risk sensing and an AI-powered supply chain assistant, with control tower capabilities in development.
This is a pivotal moment to join. As the program moves into 2027, the focus shifts from building capabilities to scaling them. You will lead one integrated portfolio, scale high-value use cases, hand mature products over to business ownership and build internal capability for the long term. Throughout, you will treat the business decision, not the technology, as the unit of transformation, and measure success by evidenced business value and sustained adoption.
Reporting to the Executive Director, Digital Supply Chain, you will lead a multi-location core team of Decision Architects, workstream leads and change and communications specialists, and direct a wider delivery network across IT, data, business services and external partners. This is a global role, working alongside our other Intelligent Supply pillars, AI Development Agent (AIDA) and Autonomous Manufacturing, to deploy technology consistently across Global Operations. You will provide the decision, data and insight capabilities that the business adopts through existing processes, while Quality, Regulatory and operational decisions remain with the accountable teams.
What you'll do
- Set the strategy: Set the SHSC vision, strategy and decision roadmap, defining which decisions to support, augment or automate, and the right level of autonomy for each. Lead annual integrated planning to deliver one prioritized, resourced portfolio.
- Spearhead the program: Lead day-to-day program management and line-manage the core team. Chair steering committees, integrated plan reviews and quarterly benefit reviews, and lead a fixed-capacity delivery model in which scope flexes to available capacity.
- Champion Decision Intelligence: Steer the Decision Architecture discipline so every use case starts from a clearly defined business decision. Shape the roadmap for our Decision Intelligence platform, including controlled write-back to ERP and planning systems and the progression from human-in-the-loop to human-on-the-loop automation, while keeping decision design platform-independent.
- Deliver measurable value: Implement a governed intake, assessment and prioritization process with clear decision gates. Build compelling business cases and track benefits through accountable business owners, measuring adoption as well as delivery.
- Build lasting capability: Grow internal Decision Architecture capability through secondments and a common accreditation pathway, and guide the move from partner-led delivery to internal ownership without disrupting work in flight.
- Engage stakeholders and partners: Build trusted relationships with senior leaders, business functions and strategic technology partners, owning partner performance, commercial value and knowledge transfer.
- Handle risk and performance: Maintain risk and KPI frameworks, lead critical dependencies such as ERP transformation, data readiness and integration architecture, and apply risk-based human oversight suited to a GxP-regulated environment.
- Lead change and adoption: Redesign roles, routines and decision rights so planners move from collecting data to managing exceptions, build trust through explainable recommendations, and transfer mature capabilities into business ownership with clear exit criteria and ongoing review of value and adoption.
Essential for the role
- Bachelor's Degree
- 10+ years leading large-scale digital transformation programs with cross-functional teams, ideally in supply chain planning or logistics.
- Deep understanding of end-to-end supply chain operations and business processes, ideally in a complex, regulated manufacturing environment.
- Experience in decision-centric design (Decision Architecture), breaking complex operational decisions into triggers, logic, trade-offs and guardrails.
- Experience leading Decision Intelligence or AI-enabled decision portfolios from MVP to scale-up and business-as-usual operation, including human-in/on-the-loop governance and write-back to ERP and planning systems.
- Management-level experience of digital supply chain platforms (e.g., ERP, APS) and a record of effective partnership with IT.
- Track record of building internal capability, moving delivery from external partners to business ownership, and shaping data and architecture demand (data products, knowledge graphs, AI-ready data).
- Experience with decision intelligence platforms
Desirable for the role
- MBA degree
- Pharmaceutical or healthcare industry experience, including the regulatory environment.
- Experience in a global role handling international supply chain challenges.
- Proficiency in Agile methods and structured project management frameworks.
- Familiarity with supply chain technologies such as OMP, SAP (including S/4HANA), Resilinc, project44, One Network, Celonis, Neo4j knowledge graphs and Optilogic.
Office Working Requirements
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
The annual base pay for this position ranges from $177,652.80 - 266,479.20 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
#LI-Hybrid
Date Posted
09-Nov-2026Closing Date
19-Nov-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
USA Jobs 24 copied this listing from AstraZeneca's official careers site on November 10, 2026 and checked it again November 10, 5:17 AM ET. AstraZeneca will never ask you to pay to apply or to buy equipment with a check they send you. If anyone does, it is a scam.
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