At a glance
AstraZeneca is hiring a Senior Maintenance Technician in United States. It is a full-time role in Engineering & Manufacturing, asking for at least 6 years of experience, first listed on November 1. The advertised pay is $71,750–$107,624 a year. AstraZeneca has 86 other openings in the US. Across all employers on USA Jobs 24 there are 611 Engineering & Mfg openings in the US today; the typical one asks for 3 years and advertises about $103,000 a year at the midpoint.
About this role
There are 2 positions available, 1 for first and 1 for 2nd shifts:
1) First shifts are 5am-1:30pm and 7am-3:30pm
2) Second Shifts are 1pm-9:30pm and 2pm-10:30pm
You’ll lead maintenance execution, troubleshoot complex utilities and equipment, and mentor teammates—all while partnering closely with Manufacturing, Quality, and Engineering.
What you’ll do:
Preventive/predictive/corrective maintenance on cleanroom HVAC, BMS/EMS, process equipment (incubators, biosafety cabinets, centrifuges, freezers, pumps, single‑use systems), and critical utilities (clean steam, chilled water, gases, compressed air). Operate and troubleshoot boilers, steam generators, cooling towers/chillers, and water treatment systems. Support cleanroom integrity (HEPA, pressure differentials, temp/RH), lead root cause analysis and CAPA, calibrate instruments, and contribute to equipment qualification (URS/IQ/OQ/PQ). Own documentation in CMMS with impeccable GDP, and champion EHS (LOTO, permits, OSHA/NFPA 70E).
What you’ll bring:
Experience: 6–10+ years in GMP biopharma or cell therapy/ATMP maintenance, including cleanrooms and regulated utilities.
Education: High School Diploma/GED, associate degree or technical diploma in Mechanical/Electrical/Mechatronics/Industrial Maintenance or equivalent military/apprenticeship training; or related field a plus.
Technical expertise: HVAC for controlled environments, clean steam/chilled water/process gases, electrical systems up to site-authorized voltage, reading P&IDs/schematics/single-line diagrams, basic PLC/HMI.
GMP savvy: cGMP, GDP, deviations/CAPA, validation/qualification for utilities.
Systems: CMMS, BMS/EMS; comfortable with digital workflows and e-logbooks.
Soft skills: Clear communication, teamwork, prioritization, and mentoring.
Nice to have: Vibration/thermography basics, manufacturer training on chillers/controls, GxP/cleanroom coursework, safety certifications.
Work environment: Cleanrooms and mechanical spaces; lift up to 50 lbs, climb ladders, work at heights, wear PPE, and support an on-call rotation.
Why this role matters: Your expertise keeps our therapeutics on track—maintaining validated systems, driving reliability, and enabling patients to receive life-changing treatments.
Ready to make an impact? Apply now and help us advance cell therapy with safe, reliable, and compliant operations.
The annual base pay (or hourly rate of compensation) for this position ranges from $71,749.60 - 107,624.40. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
28-Oct-2026Closing Date
05-Nov-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
USA Jobs 24 copied this listing from AstraZeneca's official careers site on November 1, 2026 and checked it again November 2, 5:17 AM ET. AstraZeneca will never ask you to pay to apply or to buy equipment with a check they send you. If anyone does, it is a scam.
Similar engineering & mfg jobs
Functional/BSA Lead
Atlassian
Make enhancement on the Oracle fusion, Revpro to support "Change the business". Integrate Fusion with other systems like Salesforce, Stripe billing, Zuora Revpro, Blackline, Avatax.
- San Francisco, CA
- Remote
NewSignals Discipline Lead
AECOM
We are seeking a motivated and detail-oriented Signals Discipline Lead with experience in rail and transit signal systems.
- Pittsburgh, PA
- Hybrid
- 8+ yrs
NewAvionics Test Technician, Starbase Vibe Test Lab
SpaceX
Perform acceptance (ATP) and qualification (QTP) testing of flight hardware and document results in a clear, precise and complete manner
- Starbase, TX; Brownsville, TX
- 2+ yrs
NewInstallation and Maintenance Technician
Verizon
Getting our customers connected to America's fastest and most reliable network! You'll be out and about in the neighborhoods we serve, installing, testing, repairing and maintaining the…
- Pottsville, PA
NewInstallation and Maintenance Technician
Verizon
Getting our customers connected to America's fastest and most reliable network! You'll be out and about in the neighborhoods we serve, installing, testing, repairing and maintaining the…
- Harrisburg, PA
New