Senior Global Program Manager

Career Category

Project Management

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Global Program Manager

What you will do

Let’s do this. Let’s change the world. In this vital role you will be a strategic partner to leaders of the Product Teams in the success of the strategic vision of the program.

Implementation of our strategy occurs via three cross-functional sub-teams called Work Package Teams (WPTs). The WPTs include 1) Evidence Generation Teams (EGTs) focusing on clinical development activities 2) Product Delivery Teams (PDTs) that concentrate on operations/manufacturing and supply chain activities 3) Integrated Brand Teams (IBTs) that are committed to global marketing, pricing, access, and reimbursement activities.

The Senior Global Program Manager (SPM) will drive the development, creation and implementation of high quality, global, coordinated cross-functional project plans for products in accordance with the program strategy. In addition, the SPM may be asked to lead and/or participate in special department, cross-functional, or team projects.

The SPM supports the cross-functional drug development and commercialization activities of pipeline or inline products at Amgen and will report into the Director of Global Program Management.

Role focus: Drug Development and Commercialization

This Senior Global Program Manager role provides strategic and operational program management leadership across late-stage drug development and commercialization. The SPM is a key partner to the Global Development Lead in driving the Evidence Generation Team, translating the Target Product Profile and overall program strategy into an integrated evidence-generation plan and coordinated execution across Clinical Development and Operations, Regulatory Affairs, Safety, Biostatistics, Clinical Pharmacology, Medical Affairs, Health Economics and Outcomes Research, and other relevant functions.

The SPM also works closely with the Integrated Brand Team program manager and Commercial, Medical Affairs, and Value and Access leaders to connect evidence generation and regulatory milestones with global brand planning, access strategy, launch readiness, and lifecycle opportunities.

The SPM also maintains close connectivity with the Indication Team/Product Team, which is managed by the Global Program Manager. In partnership with the Global Program Manager, the SPM ensures that Evidence Generation Team plans, decisions, risks, and deliverables are integrated into the broader indication strategy, governance roadmap, access and launch planning, and cross-work-package dependencies. The SPM supports alignment, escalation, and information flow between the Evidence Generation Team and the broader Product Team.

The successful candidate will operate as a strategic integrator across functions and teams—framing decisions, identifying interdependencies and critical-path activities, preparing decision-ready recommendations for governance, and driving accountability for milestones, risks, resources, and follow-through. This role requires the ability to translate complex scientific, operational, regulatory, access, and commercial considerations into clear, executable cross-functional plans.

Responsibilities include:

• Partners with functional leads to develop high quality, integrated, cross-functional plans for cross-functional sub-teams that are aligned with the overall program strategy
• Ensures cross-functional alignment and accountability
• Facilitates resource planning, financial and capacity assessments as needed
• Conducts the risk management and scenario planning and develops contingency and/or risk mitigation plans
• Coordinates activities with external business partners and alliances, where applicable; contributes to a successful partnership outcome Partners with the Global Development Lead and Evidence Generation Team members to drive team effectiveness, integrated evidence strategy, Clinical Development Plan execution, and delivery of the clinical and nonclinical data package required to support registration, access, and patient use.
• Partners with the Global Program Manager and Indication Team Lead to ensure that Evidence Generation Team strategy, milestones, risks, assumptions, and decisions are integrated into the overall indication plan and brought forward to the Indication Team and governance forums as needed.
• Partners with the Integrated Brand Team program manager and global Commercial, Medical Affairs, and Value and Access leaders to align evidence-generation activities and development milestones with brand strategy, payer and access needs, launch planning, and lifecycle management.
• Connects Evidence Generation Team and Integrated Brand Team plans to the overall product strategy, proactively identifying cross-team dependencies, decision points, critical-path activities, and potential downstream impacts.
• Structures complex cross-functional discussions to enable timely, evidence-based decisions; develops scenarios and recommendations; and ensures teams are prepared for governance and senior-leadership review.
• Maintains an integrated view of program milestones, risks, assumptions, resources, budgets, and functional commitments, escalating material issues with clear options and recommended actions.
• Promotes effective team operating practices, including clear objectives, roles and accountabilities, decision and action tracking, transparent communication, and timely follow-through across global matrix teams.

Ensures effectiveness of the work package teams by:

• Drives the development and timely completion of annual WPT goals and input to the Global Product Strategy
• Documents issues, decisions and action items of functional work package teams and ad hoc project team meetings
• Identifies cross-functional project issues to Global Program Manager (GPM) or cross-functional Work Package Team Lead, as appropriate

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 2 years of Relevant experience

OR

Master’s degree and 4 years of Relevant experience

OR

Bachelor’s degree and 6 years of Relevant experience

OR

Associate’s degree and 10 years of Relevant experience

OR

High school diploma / GED and 12 years of Relevant experience

Preferred Qualifications:

• Drug development experience including deep experience in one or more core drug development and commercialization functions and experience leading teams through governance process.

• Program and project management skills with experience in a healthcare-related environment, operationalizing strategic initiatives, including cross-functional strategic planning, development of integrated plans, monitoring and driving execution to plan.

• Emotional intelligence skills including influencing without authority and navigating within a matrix environment.

• Experience using Project Management tools, methodologies, practices and infrastructure, as related to the Biopharmaceutical Industry

• Experience supporting late-stage drug development, evidence generation, regulatory submission and approval, global launch planning, and/or lifecycle management for a pipeline or inline biopharmaceutical product.

• Demonstrated experience partnering with development and commercial leaders to lead or enable cross-functional teams such as an Evidence Generation Team, Development Team, Asset Team, Integrated Brand Team, Value and Access Team, or Launch Team.

• Working knowledge of the end-to-end biopharmaceutical lifecycle and the interdependencies among Clinical Development and Operations, Regulatory Affairs, Safety, Biostatistics, Clinical Pharmacology, Medical Affairs, Health Economics and Outcomes Research, Value and Access, Commercialization, and product supply.

• Demonstrated ability to synthesize scientific, operational, regulatory, financial, access, and commercial inputs into integrated plans and clear, decision-ready recommendations for senior leadership and governance.

• Experience with late-stage development and commercialization activities, including evidence planning, regulatory milestones, payer and access readiness, brand planning, launch preparation, and post-approval lifecycle opportunities.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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Salary Range

141,831.00USD -191,889.00 USD